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May 24, 2026Journal of Clinical MedicineOpen Access

Does Dynamic Compliance-Guided PEEP Titration Reduce Postoperative Pulmonary Aeration Loss in Laparoscopic Bariatric Surgery? Randomized Controlled Trial

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Authors

DGDilara GöçmenYMYasemin MasatlıoğluFÖFeyza Özaltun

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Overview

Randomized trial demonstrates reduced postoperative pulmonary aeration loss in obese patients, suggesting benefits of individualized PEEP titration.

Key Points

  • This study aims to evaluate the impact of dynamic compliance-guided PEEP titration on postoperative pulmonary aeration loss in patients undergoing laparoscopic bariatric surgery.
  • Single-center randomized controlled trial involving 70 patients with obesity (BMI ≥ 35 kg/m2)
  • Patients randomized 1:1 to either dynamic compliance-guided PEEP titration or fixed PEEP 8 cmH2O
  • Primary outcome measured was the modified lung ultrasound score (mLUSS) assessed postoperatively.
  • mLUSS was significantly lower in the dynamic group (2.20 ± 1.16) compared to the fixed group (5.80 ± 2.14; p < 0.001)
  • PaO2/FiO2 ratio was higher in the dynamic group (425.11 ± 127.13 mmHg vs. 311.65 ± 92.59 mmHg; p < 0.001)
  • Supplemental oxygen requirement was significantly lower in the dynamic compliance group (p = 0.001).

Cite This Study

Göçmen et al. (2026) studied this question.

synapsesocial.com/papers/6a1295ce48a0ea1665672156https://doi.org/10.3390/jcm15114018
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1EIT-guided individualized PEEP titration versus conventional lung-protective ventilation to prevent pulmonary complications in laparoscopic bariatric surgery: a study protocol for a randomized controlled trial2026
  2. 2Driving pressure-guided dynamic PEEP titration reduces atelectasis and improves oxygenation in pediatric laparoscopy: a randomized trial on personalized ventilation strategies2025 · 2 citations
  3. 3EIT-Guided Personalized PEEP Improves Postoperative Lung Ultrasound Scores in Patients Undergoing Metabolic Bariatric Surgery: A Randomized Controlled Trial2026
  4. 4Individualized PEEP titration guided by static lung compliance reduces postoperative atelectasis in elderly patients during laparoscopic Trendelenburg surgery: a randomized controlled trial2026
  5. 5Effect of intermittent recruitment manoeuvre combined with PEEP on postoperative atelectasis in obese patients: a randomized controlled trial2026