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May 24, 2026Drug Development Research

Nanobodies: Pioneering Next‐Generation Tools in Modern Medicine

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Authors

OFOginni Gbenga FolorunshoUniversity of Nova GoricaQFQueenie FernandesNational Center for Cancer Care and ResearchAEAyo Oisagah EzekielJoseph Ayo Babalola University

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Implication

Review highlights applications of nanobodies in therapy and diagnostics, indicating their potential in various diseases.

Key Points

  • This review aims to examine the structural and functional characteristics of nanobodies and their applications in different disease therapies.
  • Exploration of nanobody production methods in microbial systems
  • Analysis of applications in cancer, neurodegenerative diseases, and infectious diseases
  • Discussion of challenges and strategies to address limitations such as half-life and immunogenicity.
  • Nanobodies demonstrate effectiveness in targeted drug delivery and enhanced tumor imaging in cancer treatment.
  • They show potential for crossing the blood-brain barrier, aiding treatment in neurodegenerative diseases.
  • Nanobodies can neutralize toxins and modulate the immune response in inflammatory and infectious diseases.

Cite This Study

Folorunsho et al. (2026) studied this question.

synapsesocial.com/papers/6a12960648a0ea1665672691https://doi.org/10.1002/ddr.70319
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