Key result
Metabolic-bariatric surgery in patients ≥65 is linked to ~37% weight loss at 5 years and comorbidity remission.
Why the study?
Obesity complications increase with age, but older patients face a higher perioperative risk necessitating a clear risk-benefit balance for metabolic/bariatric surgery.
Does metabolic/bariatric surgery improve weight loss and remission of associated medical conditions in patients aged ≥ 65 years?
Cohort (n=111)
No
Does metabolic/bariatric surgery improve weight loss and remission of associated medical conditions in patients aged ≥ 65 years?
Metabolic/bariatric surgery in patients aged ≥ 65 years is effective for long-term weight loss and comorbidity remission, though it is associated with a 7.2% early and late complication rate.
May support consideration in selected patients ≥65 years; extends observational data but leaves open need for randomized confirmation.
Introduction Overweight and obesity have been steadily increasing worldwide. Metabolic/bariatric surgery (MBS) is the most effective treatment for obesity and its associated medical conditions. Obesity complications increase with age, however, older patients face a higher perioperative risk necessitating a clear risk-benefit balance. This study evaluated weight-loss outcomes, remission of associated medical conditions, and complications in patients aged ≥ 65 years undergoing MBS. Methods This retrospective analysis included patients aged ≥ 65 years who underwent MBS at the Medical University of Vienna between 2008 and 2025. Weight and associated medical complications were assessed at baseline and at 1, 2, and 5 years postoperatively. Early (< 30 days) and late complications up to 5 years were recorded. Results In total, 111 patients were included. Baseline weight was 125.8 ± 22.3 kg and BMI 45.2 ± 7.4 kg/ \:m² . At 5 years, mean BMI decreased to 27.5 ± 6.2 kg/ \:m² corresponding to a total weight loss of 37.3 ± 14.7%. The prevalence of type II diabetes decreased from 54.1% to 22.9% and arterial hypertension from 87.4% to 56.2%. Early and late complications each occurred in 7.2%. Conclusion MBS achieves substantial long-term weight reduction and remission of associated medical conditions. Complication rates are relatively high, underscoring careful patient selection is essential. Larger prospective studies focusing on elderly populations are warranted. Keypoints: MBS in elderly patients is effective in terms of weight loss and remission of associated medical complications. - MBS in elderly patients was associated with a relatively high complication rate. - Deaths within the study period were not associated with the MBS procedure.
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Pedarnig et al. (2026) conducted a cohort in Obesity (n=111). Metabolic-bariatric surgery (MBS) vs. Baseline was evaluated on Total weight loss (TWL) at 5 years. Metabolic-bariatric surgery in patients aged ≥ 65 years achieved a mean total weight loss of 37.3% at 5 years and substantial remission of obesity-associated medical conditions.
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