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May 24, 2026EntropyOpen Access

Effect of Ion Channel Randomness on Sensitivity of Neurons to External Electromagnetic Fields: Computational Study

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Authors

APArkady PikovskyUniversity of PotsdamADAndreas DeserFederal Office for Radiation Protection

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Implication

Computational study reveals how ion channel randomness affects neuron firing rates and patterns.

Key Points

  • This study aims to understand how randomness in ion channels influences neuron sensitivity to external electromagnetic fields.
  • Conducted stochastic simulations using Hodgkin–Huxley and Morris–Lecar models.
  • Reduced Markov process of membrane potential evolution to ordinary differential equations.
  • Employed Wiener order parameter to measure regularity in voltage time series.
  • Ion channel stochasticity significantly affects spike rates, particularly at lower external force frequencies.
  • Neural activity demonstrates resonant-like behavior in response to varying driving frequencies, peaking in the beta range.

Cite This Study

Pikovsky et al. (2026) studied this question.

synapsesocial.com/papers/6a12962948a0ea1665672bdchttps://doi.org/10.3390/e28060581
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