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May 24, 2026The American Journal of Sports Medicine

Association Between Autograft Choice and Risk of Contralateral ACL Injury in Patients ≤25 Years of Age: A Systematic Review and Meta-analysis

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Authors

CPCamryn B. PetitZHZaamin B. HussainRLRhodri S. Lloyd

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Overview

Systematic review compares contralateral ACL injury rates by graft type in young patients, suggesting sex differences in risk profiles.

Key Points

  • This research aims to understand how different autograft types affect the risk of contralateral ACL injuries in young patients after reconstruction.
  • Performed a systematic review and meta-analysis of 22 studies
  • Included patients ≤25 years old with a minimum follow-up of 24 months
  • Evaluated contralateral ACL injury rates by graft type: hamstring tendon, bone–patellar tendon–bone, and quadriceps tendon.
  • Pooled contralateral ACL injury rates were 10.8% for hamstring tendon, 10.5% for bone-patellar tendon-bone, and 12.2% for quadriceps tendon.
  • No significant differences in injury rates among graft types (χ² = 0.7; P = .7).
  • Males had a significantly lower risk of contralateral ACL injury after BPTB graft compared to females (RR, 0.439).

Cite This Study

Petit et al. (2026) studied this question.

synapsesocial.com/papers/6a12963748a0ea1665672e47https://doi.org/10.1177/03635465261440398
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