Investigates glutathione peroxidase's role in virulence under oxidative stress in bacteria, indicating its significance.
BACKGROUND: relies on antioxidant enzymes to withstand host-derived oxidative stress during infection. Here, we investigated the role of bacterial glutathione peroxidase (GPx) in survival and virulence of the PA14 strain under inflammatory conditions associated with hyperuricemia. METHODS: strains to assess bacterial burden, inflammation, oxidative damage, and survival. RESULTS: resistance to oxidative killing and promoting virulence. CONCLUSION: .
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Cordeiro et al. (2026) studied this question.
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