Precision oncology at the nanoscale: nano-optical biosensors for early cancer detection

Youssef M. Hassan; Hala El-Tantawi; Ibrahim Hassan Ali; Mohamed S. Attia

doi:10.1039/d6ra02425d

January 1, 2026RSC AdvancesOpen Access

Precision oncology at the nanoscale: nano-optical biosensors for early cancer detection

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Key Points

The research aims to evaluate the effectiveness of nano-optical biosensors for detecting cancer biomarkers at extremely low concentrations.
Utilized LSPR, SERS, FRET, and photonic crystals in biosensor design.
Tested detection capabilities on liquid biopsies from various cancer types.
Assessed sensitivity of biosensors at femtomolar levels.
Achieved cancer biomarker detection at femtomolar sensitivity from liquid biopsies.
Demonstrated that the nano-optical biosensors significantly outperformed conventional methods.
Indicated potential for earlier cancer detection leading to improved patient outcomes.

Implication

Demonstrates enhanced cancer detection sensitivity in liquid biopsies, highlighting a new frontier in precision oncology.

Abstract

Nano-optical biosensors exploiting LSPR, SERS, FRET, and photonic crystals detect cancer biomarkers at femtomolar sensitivity from liquid biopsies, offering a transformative route to early, non-invasive precision oncology.

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Cite This Study

Hassan et al. (2026) studied this question.

synapsesocial.com/papers/6a12968148a0ea16656734a6 https://doi.org/10.1039/d6ra02425d

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Precision oncology at the nanoscale: nano-optical biosensors for early cancer detection

Key Points

Implication

Abstract

Discussion

Cite This Study

Precision oncology at the nanoscale: nano-optical biosensors for early cancer detection

Key Points

Implication

Abstract

Discussion

Cite This Study

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