What question did this study set out to answer?

This study aims to evaluate the effectiveness and safety of mHealth-supported versus centre-based cardiac rehabilitation using HIIT in patients with stable coronary heart disease.

May 24, 2026BMC Cardiovascular DisordersOpen Access

Comparison of mHealth-supported and centre-based cardiac rehabilitation in patients with stable coronary heart disease: a randomized controlled trial

Q: What are the key findings of this study?

mHealth-supported high-intensity interval training significantly improved peak VO2 (20.12 vs. 16.70 ml/kg/min) compared to centre-based training in patients with stable coronary heart disease.

Q: What is the clinical evidence from this study?

Study design: RCT. Population: Stable coronary heart disease (n=98). Intervention: mHealth-supported home-based high-intensity interval training (HIIT) vs. Centre-based supervised HIIT. Primary outcome: Peak VO2 (ml/kg/min) (p=<0.001).

Q: What does this research mean for the field?

mHealth-supported home-based high-intensity interval training (HIIT) yields greater improvements in cardiopulmonary function, exercise capacity, and quality of life compared to centre-based HIIT in patients with stable coronary heart disease. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

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Key result

mHealth-supported HIIT improves peak VO2 by ~20% versus centre-based training in stable CHD.

P<0.001
n=98

Why the study?

Participation in centre-based cardiac rehabilitation is suboptimal, and evidence comparing delivery models of high-intensity interval training (HIIT) remains limited.

Does mHealth-supported home-based HIIT improve cardiopulmonary function, exercise capacity, and quality of life compared to centre-based HIIT in adults with stable CHD?

Population

98 adults with stable CHD eligible for Phase II cardiac rehabilitation

Comparison

mHealth-supported home-based HIIT vs supervised centre-based HIIT

Design

Randomized controlled trial

Authors

杨杨晓冰Handan College JLJing LiangHandan College YLYuling LiHandan College

Discussion

Member takes

Implication

Supports mHealth-supported HIIT over centre-based training for peak VO2 gains in stable CHD; extends RCT evidence to scalable home-based cardiac rehabilitation.

Key Points

This study aims to evaluate the effectiveness and safety of mHealth-supported versus centre-based cardiac rehabilitation using HIIT in patients with stable coronary heart disease.
Conducted a randomized controlled trial involving 98 adults with stable CHD.
Participants were randomly assigned to either mHealth-supported home training or centre-based rehabilitation.
Primary outcomes assessed included 6MWD, CPET parameters, and SF-36 quality of life scores.
The intervention group showed significant improvements in sleep quality scores (3.17 vs. 4.83, P < 0.05).
There were higher peak METs in the intervention group (5.83 vs. 4.94, P < 0.05) and greater anaerobic threshold METs (4.29 vs. 3.53, P < 0.05).
The 6MWD was significantly higher in the intervention group (563.83 vs. 531.49 m, P < 0.05).

Study Design

Type

RCT (n=98)

Blinding

Assessor-blind

Randomization

Computer-generated random sequence

Multicenter

Structured PICO

Does mHealth-supported home-based HIIT improve cardiopulmonary function, exercise capacity, and quality of life compared to centre-based HIIT in adults with stable CHD?

Population

98 adults with stable coronary heart disease (CHD) eligible for Phase II cardiac rehabilitation

Intervention

mHealth-supported home-based high-intensity interval training (HIIT) with real-time monitoring and individualized feedback via the Xin’ankang mHealth platform

Comparator

Supervised centre-based rehabilitation performing the same standardized HIIT protocol

Outcome

Six-minute walk distance (6MWD), cardiopulmonary exercise testing (CPET) parameters, and SF-36 quality of life scoressurrogate

Main Result

Absolute Event Rate: 20.12% vs 16.7%

p-value: p=<0.001

mHealth-supported home-based HIIT provides greater improvements in cardiopulmonary function and exercise capacity than traditional centre-based HIIT in patients with stable CHD.

Limitations

Single-center trial
Participants and exercise supervisors were not blinded
Adherence was measured using different methods between groups

Cite This Study

杨晓冰 et al. (2026) conducted an RCT in Stable coronary heart disease (n=98). mHealth-supported home-based high-intensity interval training (HIIT) vs. Centre-based supervised HIIT was evaluated on Peak VO2 (ml/kg/min) (p=<0.001). mHealth-supported high-intensity interval training significantly improved peak VO2 (20.12 vs. 16.70 ml/kg/min) compared to centre-based training in patients with stable coronary heart disease.

synapsesocial.com/papers/6a1298b248a0ea1665674054 https://doi.org/10.1186/s12872-026-05991-7

Topics

Coronary artery disease

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Implication

Supports mHealth-supported HIIT over centre-based training for peak VO2 gains in stable CHD; extends RCT evidence to scalable home-based cardiac rehabilitation.

Comparison of mHealth-supported and centre-based cardiac rehabilitation in patients with stable coronary heart disease: a randomized controlled trial

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Topics

Comparison of mHealth-supported and centre-based cardiac rehabilitation in patients with stable coronary heart disease: a randomized controlled trial

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Also Consider

Topics

Also Consider