What is the clinical evidence from this study?

Study design: Observational. Population: Coronary bifurcational lesions (n=67). Intervention: PTCA of major branches without protection of large side branches. Primary outcome: Side branch occlusion.

What does this research mean for the field?

Angioplasty of bifurcational lesions without side branch protection can be effectively performed with a low rate of complications, resulting in side branch occlusion in 14.5% of branches and leaving 89% of patients asymptomatic at 2.2 years. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the procedural safety, occlusion risk, and clinical outcomes of performing coronary angioplasty on bifurcation lesions without mechanical protection of large side branches.

November 1, 1992Catheterization and Cardiovascular Diagnosis

Coronary angioplasty of bifurcational lesions without protection of large side branches

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Key result

Angioplasty of bifurcational lesions without side branch protection resulted in side branch occlusion in 10 of 69 branches (14.5%), with 89% of patients asymptomatic at 2.2 years.

Why the study?

Does PTCA of major branches without protection of large side branches result in acceptable safety and clinical outcomes in patients with bifurcational lesions?

Population

67 patients with bifurcational lesions and large side branches, including 32 with unstable angina and 35…

Design

Cohort

Follow-up

2.2 years

Authors

RCRenzo CiampricottiRadboud University Nijmegen MGMamdouh El GamalRadboud University Nijmegen BGBerry van GelderRadboud University Nijmegen

Discussion

Member takes

Implication

May support provisional bifurcation PTCA without routine side branch protection; leaves open randomized confirmation before practice change.

Key Points

To evaluate the procedural safety, occlusion risk, and clinical outcomes of performing coronary angioplasty on bifurcation lesions without mechanical protection of large side branches.
Evaluated 67 patients (50 men, mean age 55 years; 32 unstable angina, 35 stable angina) with bifurcation lesions involving 69 large side branches (≥1.8 mm) treated without side branch protection.
Tracked acute procedural success, side branch compromise, rescue recanalization rates, and clinical endpoints across a mean follow-up period of 2.2 years.
Main branch angioplasty succeeded in 66 of 67 patients (1 required emergency bypass surgery), with side branch occlusion occurring in 10 cases (5 were asymptomatic, and 4 of 5 symptomatic occlusions were successfully recanalized).
Only one patient suffered a non-Q-wave myocardial infarction, and at 2.2 years of follow-up, 60 patients (89%) remained completely asymptomatic with favorable angiographic or exercise test results.

Study Design

Type

Observational (n=67)

Structured PICO

Does PTCA of major branches without protection of large side branches result in acceptable safety and clinical outcomes in patients with bifurcational lesions?

Population

67 patients (50 men) with bifurcational lesions and large (>= 1.8 mm) side branches, including 32 with unstable angina and 35 with stable angina, mean age 55 years (range 31-77).

Intervention

Percutaneous transluminal coronary angioplasty (PTCA) of major branches without protection of lesion-associated large side branches.

Outcome

Risk and clinical relevance of side branch (SB) occlusion during angioplastysafety

Angioplasty of bifurcational lesions without side branch protection can be performed with a low rate of complications and favorable long-term outcomes.

Cite This Study

Ciampricotti et al. (1992) conducted an observational in Coronary bifurcational lesions (n=67). PTCA of major branches without protection of large side branches was evaluated on Side branch occlusion. Angioplasty of bifurcational lesions without side branch protection resulted in side branch occlusion in 10 of 69 branches (14.5%), with 89% of patients asymptomatic at 2.2 years.

synapsesocial.com/papers/6a129af21d9aa3bb4e346879 https://doi.org/10.1002/ccd.1810270307

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November 1, 1992Catheterization and Cardiovascular Diagnosis

Coronary angioplasty of bifurcational lesions without protection of large side branches

View Full Paper

Ask AI

Bookmark

Key result

Angioplasty of bifurcational lesions without side branch protection resulted in side branch occlusion in 10 of 69 branches (14.5%), with 89% of patients asymptomatic at 2.2 years.

Why the study?

Does PTCA of major branches without protection of large side branches result in acceptable safety and clinical outcomes in patients with bifurcational lesions?

Population

67 patients with bifurcational lesions and large side branches, including 32 with unstable angina and 35…

Design

Cohort

Follow-up

2.2 years

Authors

RCRenzo CiampricottiRadboud University Nijmegen MGMamdouh El GamalRadboud University Nijmegen BGBerry van GelderRadboud University Nijmegen

Discussion

Member takes

Implication

May support provisional bifurcation PTCA without routine side branch protection; leaves open randomized confirmation before practice change.

Key Points

To evaluate the procedural safety, occlusion risk, and clinical outcomes of performing coronary angioplasty on bifurcation lesions without mechanical protection of large side branches.
Evaluated 67 patients (50 men, mean age 55 years; 32 unstable angina, 35 stable angina) with bifurcation lesions involving 69 large side branches (≥1.8 mm) treated without side branch protection.
Tracked acute procedural success, side branch compromise, rescue recanalization rates, and clinical endpoints across a mean follow-up period of 2.2 years.
Main branch angioplasty succeeded in 66 of 67 patients (1 required emergency bypass surgery), with side branch occlusion occurring in 10 cases (5 were asymptomatic, and 4 of 5 symptomatic occlusions were successfully recanalized).
Only one patient suffered a non-Q-wave myocardial infarction, and at 2.2 years of follow-up, 60 patients (89%) remained completely asymptomatic with favorable angiographic or exercise test results.

Study Design

Type

Observational (n=67)

Structured PICO

Does PTCA of major branches without protection of large side branches result in acceptable safety and clinical outcomes in patients with bifurcational lesions?

Population

67 patients (50 men) with bifurcational lesions and large (>= 1.8 mm) side branches, including 32 with unstable angina and 35 with stable angina, mean age 55 years (range 31-77).

Intervention

Percutaneous transluminal coronary angioplasty (PTCA) of major branches without protection of lesion-associated large side branches.

Outcome

Risk and clinical relevance of side branch (SB) occlusion during angioplastysafety

Angioplasty of bifurcational lesions without side branch protection can be performed with a low rate of complications and favorable long-term outcomes.

Cite This Study

synapsesocial.com/papers/6a129af21d9aa3bb4e346879 https://doi.org/10.1002/ccd.1810270307

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