Key result
Higher cardiovascular risk factor-adjusted TG/HDL-C ratio is associated with stiffer vessels in youth, particularly in obese subjects.
Why the study?
Does a higher TG/HDL-C ratio predict increased arterial stiffness in children, adolescents, and young adults?
Observational
Does a higher TG/HDL-C ratio predict increased arterial stiffness in children, adolescents, and young adults?
Evaluating the TG/HDL-C ratio may be a useful noninvasive marker to identify youth, particularly those who are obese, at risk for early atherosclerosis.
TG/HDL-C ratio may mark stiffness in obese youth; hypothesis-generating and requires longitudinal validation before clinical use.
The triglyceride to highdensity lipoprotein cholesterol ratio (TG/HDL-C) estimates atherogenic small, dense low-density lipoprotein cholesterol and predicts arterial stiffness and hard cardiovascular events in adults.Whether TG/HDL-C predicts intermediate noninvasive end points (arterial stiffness) in youth is not known. WHAT THIS STUDY ADDS:This study is the first to document stiffer vessels in youth with higher cardiovascular risk factoradjusted TG/HDL-C, with the effect especially strong in obese subjects.Evaluating TG/HDL-C may be helpful in identifying young subjects at risk for obesity-related atherosclerosis.
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A 2013 study conducted an observational in Arterial stiffness. Triglyceride to HDL-C ratio (TG/HDL-C) was evaluated on Arterial stiffness. Higher cardiovascular risk factor-adjusted TG/HDL-C ratio is associated with stiffer vessels in youth, particularly in obese subjects.
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