The Epidemiology of Cancer Therapy

Alvan R. Feinstein

doi:10.1001/archinte.1969.00300130105014

March 1, 1969Archives of Internal Medicine

The Epidemiology of Cancer Therapy

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Key Points

To examine how understanding the untreated course and natural history of disease informs therapeutic choices and decision-making in clinical oncology.
Reviewed historical and clinical perspectives on the observation and interpretation of untreated disease trajectories.
Assessed the influence of logical fallacies, including post hoc ergo propter hoc reasoning, on historical evaluations of therapeutic efficacy.
Accurate knowledge of how a disease progresses without intervention is essential for deciding when to initiate, modify, or withhold therapies.
Misinterpreting self-limiting conditions historically led clinicians to falsely attribute spontaneous patient recovery to ineffective medical interventions.

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Implication

Methodological review explores the role of disease natural history in evaluating cancer treatments, highlighting challenges in discerning true therapeutic benefits from spontaneous recovery.

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Alvan R. Feinstein (1969) studied this question.

synapsesocial.com/papers/6a12abd392637892a9a707b8 https://doi.org/10.1001/archinte.1969.00300130105014

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The Epidemiology of Cancer Therapy

Key Points

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Implication

Discussion

Cite This Study

The Epidemiology of Cancer Therapy

Key Points

No abstract yet

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Implication

Discussion

Cite This Study

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