Key result
Fragmented QRS on a routine 12-lead ECG serves as a significant marker of myocardial scar and an independent predictor of mortality and adverse arrhythmic events across various cardiac conditions.
Why the study?
Fragmented QRS is an important, yet often overlooked marker of mortality and arrhythmic events across cardiac diseases that can be easily recorded on surface ECG.
Does fragmented QRS on surface ECG predict mortality and arrhythmic events in patients with cardiac diseases?
Does fragmented QRS on surface ECG predict mortality and arrhythmic events in patients with cardiac diseases?
Fragmented QRS on a surface ECG is a useful and accessible marker for predicting mortality and arrhythmic events in various cardiac conditions.
Should not yet change practice; supports prospective validation of fragmented QRS for arrhythmic risk stratification.
Fragment QRS (fQRS) complex is a myocardial conduction abnormality that indicates myocardial scar. It is defined as additional notches in the QRS complex. Though initially fQRS was defined in the setting of normal QRS duration (<120 m s), later it has been expanded to include conditions with wide QRS complexes as in bundle branch block, ventricular ectopy and paced rhythm, when more than 2 notches are present. It is an important, yet often overlooked marker of mortality and arrhythmic events in many cardiac diseases. The significance of fQRS lies in the fact that it just requires a surface ECG for its recording and the value of information about the condition of the heart it dispenses based on the clinical setting. We review the role of fQRS in predicting adverse cardiac events in various conditions.
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Supreeth et al. (2019) conducted a review in Cardiac diseases. Fragmented QRS (fQRS) vs. Absence of fQRS was evaluated. Fragmented QRS on a routine 12-lead ECG serves as a significant marker of myocardial scar and an independent predictor of mortality and adverse arrhythmic events across various cardiac conditions.
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