What question did this study set out to answer?

To evaluate the emergence and profile of behavioral, psychiatric, and personality disorders in patients with Parkinson's disease successfully treated with bilateral subthalamic nucleus stimulation.

June 1, 2002Journal of Neurology Neurosurgery & PsychiatryOpen Access

Behavioural disorders, Parkinson's disease and subthalamic stimulation

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To evaluate the emergence and profile of behavioral, psychiatric, and personality disorders in patients with Parkinson's disease successfully treated with bilateral subthalamic nucleus stimulation.
Retrospectively assessed N=24 patients with Parkinson's disease treated with bilateral subthalamic nucleus (STN) deep brain stimulation.
Evaluated outcomes using the Social Adjustment Scale (SAS), psychiatric interviews, the Mini International Neuropsychiatric Inventory, and the Iowa Scale of Personality Changes.
Parkinsonian motor disability improved by 69.5%, and the levodopa equivalent daily dosage decreased by 60.5%.
Social adjustment was moderately impaired in 14 patients and severely impaired in 1 patient, while 15 patients developed mild to moderate emotional hyperreactivity.
Psychiatric disorders involved decompensation of pre-existing conditions, including generalized anxiety (n=18) and depressive episodes (n=4), with personality traits aggravated in 8 patients.

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Implication

Retrospective study reveals persistent or worsened behavioral disorders in Parkinson's disease treated with subthalamic stimulation, highlighting the necessity of psychiatric screening.

Cite This Study

Jean Luc Houeto (2002) studied this question.

synapsesocial.com/papers/6a12b192e407b26696356d53 https://doi.org/10.1136/jnnp.72.6.701

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Implication

Retrospective study reveals persistent or worsened behavioral disorders in Parkinson's disease treated with subthalamic stimulation, highlighting the necessity of psychiatric screening.

Behavioural disorders, Parkinson's disease and subthalamic stimulation

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Discussion

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Cite This Study

Behavioural disorders, Parkinson's disease and subthalamic stimulation

Key Points

Discussion

Implication

Cite This Study

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