Key result
Endomyocardial biopsy holds an unclear role in pediatric myocarditis and DCM with complications reaching ~15%.
Why the study?
Due to its invasiveness and complication rate ranging from 1 to 15%, the role of endomyocardial biopsy in the diagnostic work-up of pediatric heart failure is not well established.
What is the role of endomyocardial biopsy in the diagnostic work-up of children presenting with severe left ventricular dysfunction?
What is the role of endomyocardial biopsy in the diagnostic work-up of children presenting with severe left ventricular dysfunction?
This review aims to define the diagnostic role of endomyocardial biopsy in pediatric patients with severe left ventricular dysfunction, balancing its utility against a 1-15% complication rate.
Answers are grounded in this paper and cite their sources.
Endomyocardial biopsy's unclear role in pediatric severe LV dysfunction warrants caution; leaves open need for less invasive diagnostics.
Endomyocardial biopsy (EMB) is a well-known diagnostic tool for the investigation and treatment of myocardial diseases and remains the gold standard for the diagnosis of myocarditis. Due to its invasiveness, with a complication rate ranging from 1 to 15%, its role in the diagnostic work-up of pediatric heart failure is not well established. The aim of this review is to define the role of EMB as diagnostic technique in the work up of children presenting with severe left ventricular dysfunction with the support of our center experience.
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Pilati et al. (2022) conducted a review in Pediatric Myocarditis and Dilated Cardiomyopathy. Endomyocardial biopsy was evaluated. Endomyocardial biopsy for diagnosing pediatric myocarditis and dilated cardiomyopathy has an unclear role due to its invasiveness, with a complication rate ranging from 1 to 15%.
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