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December 13, 2025Brain SciencesOpen Access

The Neural Contributions to Reactive Balance Control: A Scoping Review of EEG, fNIRS, MRI, and PET Studies

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Why the study?

Rapid postural reactions prevent falls, but the neural systems supporting these responses are not fully understood, particularly regarding aging and neurological disorders.

What are the cortical and subcortical mechanisms underlying reactive balance and how are they altered by aging and pathology?

Design

Scoping review

Key result

A scoping review of 61 neuroimaging studies demonstrated that reactive balance relies on a distributed cortico-subcortical network, with aging and pathology heightening cortical activation.

Authors

AMAndrew S. MonaghanTTTaylor N. TaklaEOEdward Ofori

Discussion

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Overview

Does not support changes to clinical balance training; leaves open hypothesis-driven trials on cortical compensation in aging and disease.

Structured PICO

What are the cortical and subcortical mechanisms underlying reactive balance and how are they altered by aging and pathology?

P
Population
61 neuroimaging studies (EEG n = 45; MRI n = 9; fNIRS n = 8; PET n = 1) examining neural activity during experimentally induced balance perturbations
I
Intervention
Experimentally induced balance perturbations assessed via neuroimaging (EEG, fNIRS, MRI, PET)
O
Outcome
Patterns of regional neural activation and age- or disease-related differencessurrogate

Reactive balance relies on a distributed cortico-subcortical network, and increased cortical activation in aging and neurological conditions suggests reduced automaticity and greater reliance on compensatory control.

Cite This Study

Monaghan et al. (2025) conducted a review in Reactive balance control (n=61). Neuroimaging (EEG, MRI, fNIRS, PET) was evaluated on Patterns of regional activation and age- or disease-related differences. A scoping review of 61 neuroimaging studies demonstrated that reactive balance relies on a distributed cortico-subcortical network, with aging and pathology heightening cortical activation.

synapsesocial.com/papers/6a12b98a257f24f1de9e2e0chttps://doi.org/10.3390/brainsci15121330
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