Key result
Achieving an optimal stent-like result following balloon angioplasty improved 8-year survival without serious cardiac events compared to suboptimal results (83% vs 58%).
Why the study?
Does achieving an optimal stent-like result from balloon angioplasty improve long-term survival without serious cardiac events compared to suboptimal results in patients undergoing elective balloon angioplasty?
Cohort (n=108)
Does achieving an optimal stent-like result from balloon angioplasty improve long-term survival without serious cardiac events compared to suboptimal results in patients undergoing elective balloon angioplasty?
Achieving a stent-like result (<25% residual stenosis) after balloon angioplasty significantly reduces restenosis and improves 8-year event-free survival compared to suboptimal results.
May support targeting optimal balloon angioplasty results; leaves open need for randomized confirmation.
This study evaluated the long-term prognosis of optimal 'stent-like' results, suboptimal results and failure of balloon angioplasty. The clinical data of 108 patients were examined during 8 years following balloon angioplasty. Based on the angiographic results, the patients were divided into 3 groups: Group A (n=59), <25% residual stenosis (ie, optimal stent-like result); Group B (n=43), 26-50% residual stenosis or large dissection (ie, suboptimal result); and Group C (n=6), >50% residual stenosis or stenosis could not be crossed (ie, failed angioplasty). Restenosis occurred in 20 of 43 patients (46.5%) in Group B, but only in 18 of 59 patients (30.4%) in Group A. Achieving stent-like results following balloon angioplasty significantly reduced the incidence of restenosis. Kaplan-Meier curves at 8 years demonstrated a survival rate without serious cardiac events of 83% in patients with stent-like results compared with 58% in those with suboptimal results and 17% in those with failed balloon angioplasty. In conclusion, the major finding of this study is that achieving stent-like results following balloon angioplasty reduces the incidence of restenosis, and 8-year survival without serious cardiac events after balloon angioplasty is significantly better in patients who have a stent-like result.
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Fukuzawa et al. (1999) conducted a cohort in Coronary stenosis requiring balloon angioplasty (n=108). Optimal stent-like result (<25% residual stenosis) vs. Suboptimal result (26-50% residual stenosis) or failed angioplasty was evaluated on Survival without serious cardiac events at 8 years. Achieving an optimal stent-like result following balloon angioplasty improved 8-year survival without serious cardiac events compared to suboptimal results (83% vs 58%).
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