Key result
A proposed pathophysiological model for ischemic heart disease shifts the clinical focus from obstructive coronary atherosclerosis to the myocardial cell to better address multifactorial ischemia.
This review challenges the traditional stenosis-centric view of ischemic heart disease, advocating for a multifactorial, cardiomyocyte-centered pathophysiological model.
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Marzilli et al. (2012) conducted a review in Ischemic heart disease. A proposed pathophysiological model for ischemic heart disease shifts the clinical focus from obstructive coronary atherosclerosis to the myocardial cell to better address multifactorial ischemia.
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