What question did this study set out to answer?

This research aims to identify reasons for nonadherence to antiretroviral therapy among HIV-infected women.

March 21, 2014Open Access

Appreciating Reasons for Nonadherence in Women

JOJennifer G. OkonskyCenters for Disease Control and Prevention AWAllison R. WebelThe University of Melbourne CRCarol Dawson RoseBC Mental Health & Substance Use Services

Key Points

This research aims to identify reasons for nonadherence to antiretroviral therapy among HIV-infected women.
Surveyed 206 women aged 15-24 on antiretroviral therapy
Analyzed reasons for missing medications using odds ratios and confidence intervals
Compared reasons for nonadherence between adherent and nonadherent women
Women reported forgetfulness as a reason for missing medications 2.2 times more than other issues (OR = 2.2, 95% CI = 1.63, 2.94, p <.001)
Significant differences in reasons for nonadherence were identified between the adherent and nonadherent groups (p <.001, 95% CI = -3.82, -2.03)
The findings highlight the need for patient-centered approaches to address types of nonadherence.

Abstract

Women aged 15-24 years have an HIV infection rate twice that of men the same age. In this study we examined reasons why HIV-infected women taking antiretroviral therapy (ART) report missing HIV medications. Women (N = 206) on ART were 2.2 times more likely to endorse reasons pertaining to forgetfulness versus reasons pertaining to problems taking pills (OR = 2.2, 95% CI = 1.63, 2.94, p <.001). There was a difference between the adherent and nonadherent groups in types of reasons overall (p <.001, 95% CI = -3.82, -2.03). Using a patient-centered approach to understand type of nonadherence (intentional vs. unintentional) may support development of novel interventions.

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