Key result
Chronic heart failure was associated with lower total bone mineral density compared to non-CHF patients, with greater reductions observed in patients with NYHA class III or IV (SMD -0.87).
Why the study?
Is chronic heart failure associated with lower bone mineral density compared to non-CHF patients?
Meta-Analysis (n=795)
Is chronic heart failure associated with lower bone mineral density compared to non-CHF patients?
Effect estimate: SMD -0.62 (NYHA I/II) and -0.87 (NYHA III/IV)
Chronic heart failure is associated with lower bone mineral density, with greater reductions seen in more severe heart failure (NYHA III/IV).
Authors
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CHF patients, especially NYHA III/IV, may warrant BMD screening; leaves open causality and whether HF therapy improves bone density.
Xing et al. (2018) conducted a meta-analysis in Chronic heart failure (n=795). Chronic heart failure vs. Non-CHF patients was evaluated on Total bone mineral density (BMD) (SMD -0.62 (NYHA I/II) and -0.87 (NYHA III/IV)). Chronic heart failure was associated with lower total bone mineral density compared to non-CHF patients, with greater reductions observed in patients with NYHA class III or IV (SMD -0.87).
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