Key result
Surgical resection of pediatric cardiac myxomas is associated with ~4% early mortality and recurrence.
Why the study?
Primary cardiac tumors are rare and cardiac myxomas account for the majority, but most reports in the literature are limited to case reports.
Does surgical excision of cardiac myxoma in children provide safe and effective long-term outcomes?
Observational (n=23)
No
Does surgical excision of cardiac myxoma in children provide safe and effective long-term outcomes?
Surgical excision of rare pediatric cardiac myxomas is associated with low recurrence rates and excellent long-term functional recovery.
Supports low-risk resection in pediatric myxomas; leaves open confirmation of long-term safety in larger prospective cohorts.
BACKGROUND: Primary cardiac tumors are rare, and cardiac myxoma (CM) accounts for the majority of these tumors. Most of the reports in the literature are case reports. This study summarizes our clinical experience in the surgical treatment of CM over the past 12 years. METHODS: We retrospectively analyzed the clinical data of 23 children with CM(8 boys, 15 girls; median age: 8.92 months, range: 2 years 5 months-12 years 9 months; body weight: 11-45 kg, median body weight: 28.21 kg) admitted to our hospital in the previous 12 years, and we statistically analyzed their clinical manifestations and surgical methods. RESULTS: 23 cases underwent myxoma excision under cardiopulmonary bypass(CPB). The follow-up period was 0.2 to 12.6 years (mean:7.2 years). Two patients could not be traced, and the follow-up completion rate was 91.30%. One patient (4.35%) died of myocardial infarction early after surgery with low continuous cardiac output. There were no cerebral embolism, acute heart failure, atrioventricular block and other related complications in 19 cases. A patient with cerebral infarction complicated with right hemiplegia recovered well after rehabilitation treatment. There was no recurrence of CM in 19 cases and all patients recovered after surgery. One patient relapsed 5 years after surgery, and no tumor recurrence was observed after the second surgery. Among the 20 long-term survivors, 13 (65.00%) were NYHA Class I patients and 7(35.00%) were NYHA Class II patients. CONCLUSIONS: Although CM in children is rare, it may cause cerebral infarction and other multi-organ embolism. Once CM is found and removed as soon as possible, it can reduce serious complications. If the complete resection is possible, surgery provides better palliation. Follow-up echocardiographic should be paid attention to after surgery.
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Zhao et al. (2023) conducted an observational in Pediatric cardiac myxoma (n=23). Surgical resection under cardiopulmonary bypass was evaluated on Mortality. Surgical resection of pediatric cardiac myxomas resulted in one early death (4.35%) and one recurrence (4.35%) among 23 patients over a mean follow-up of 7.2 years.