Key result
Adjunctive group physical activity significantly improved physical quality of life compared to pharmacological therapy alone in women with treatment-resistant major depressive disorder.
Why the study?
Does physical activity improve quality of life in women with treatment-resistant major depressive disorder?
Population
30 female patients, aged 40-60 years, with Major Depressive Disorder resistant to ongoing treatment.
Comparison
Pharmacological treatment plus physical activity… vs Pharmacological therapy alone.
Design
RCT, Randomized after stratification for comorbidity with anxiety disorders…
Follow-up
32 weeks
Authors
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Supports adjunctive group exercise for physical QoL in women with treatment-resistant MDD; extends prior objective benefits to subjective measures.
RCT (n=30)
Stratified by comorbidity with anxiety disorders
No
Does physical activity improve quality of life in women with treatment-resistant major depressive disorder?
Absolute Event Rate: 12.9% vs 10.5%
p-value: p=<0.05
Adjunctive group physical activity significantly improves the perceived physical quality of life in women with treatment-resistant major depressive disorder.
Carta et al. (2008) conducted an RCT in Major Depressive Disorder (n=30). Group physical activity vs. Pharmacological therapy alone was evaluated on WHOQOL-Bref Physical health score at 32 weeks (p=<0.05). Adjunctive group physical activity significantly improved physical quality of life compared to pharmacological therapy alone in women with treatment-resistant major depressive disorder.
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