This working group report outlines new research directions and recommendations for studying the pathophysiology of obesity-associated cardiovascular disease.
Highlights urgent need for obesity-CVD research amid epidemic; establishes new directions for synergistic pathophysiology models.
T he ongoing obesity epidemic and its impending cardio- vascular consequences represent a serious public health problem with worrisome implications for medical treatment.The urgency of providing new research directions recently led the National Heart, Lung, and Blood Institute (NHLBI) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to convene a Working Group on the Pathophysiology of Obesity-Associated Cardiovascular Disease.Gathered at this meeting were researchers with substantial experience and expertise in either obesity-related sciences, including epidemiology, endocrinology, and metabolism, or cardiovascular sciences, including cardiology, neurobiology, hematology, renal function, and pediatrics.This report is the culmination of the blending of ideas during the 2-day meeting.The resulting research recommendations include the development of new models and synergistic approaches to basic studies of obesity-associated cardiovascular diseases.
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Eckel et al. (2002) conducted a review in Obesity-associated cardiovascular disease. A joint NHLBI and NIDDK working group report outlines research recommendations for developing new models and synergistic approaches to study the pathophysiology of obesity-associated cardiovascular disease.
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