What question did this study set out to answer?

This study aims to compare left ventricular stroke volumes measured by two-dimensional echocardiography with thermodilution and cineangiography in both normal and ischemic states.

January 1, 1981Catheterization and Cardiovascular Diagnosis

Two‐dimensional echocardiographic assessment of left ventricular stroke volume: Experimental correlation with thermodilution and cineangiography in normal and ischemic states

Q: What does this research mean for the field?

Two-dimensional echocardiography accurately quantifies left ventricular stroke volume in both normal and ischemic states, demonstrating strong correlation with thermodilution and cineangiography when appropriate cross-sectional levels are used. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

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Why the study?

Does two-dimensional echocardiography accurately measure left ventricular stroke volume compared to thermodilution and cineangiography in normal and ischemic closed-chest dogs?

Population

Closed-chest dogs before and one hour after proximal LAD occlusion (N=22; 14 normal, 8 ischemic)

Comparison

Two-dimensional echocardiography using Simpson's… vs Thermodilution and cineangiography measurements

Design

Preclinical

Follow-up

1 hour after proximal LAD occlusion

Authors

PGPascal GuéretCedars-Sinai Medical Center SMSamuel MeerbaumCardiac Imaging WZWerner ZwehlMünchen Klinik Schwabing

Discussion

Member takes

Implication

Supports 2D echo validation in canine ischemia; leaves open human translation before clinical use.

Key Points

This study aims to compare left ventricular stroke volumes measured by two-dimensional echocardiography with thermodilution and cineangiography in both normal and ischemic states.
Closed-chest dogs underwent measurements before and one hour after proximal LAD occlusion.
Stroke volume was calculated using Simpson's rule and a simplified formula based on short-axis areas.
Correlations between echocardiographic measurements and reference methods were assessed.
The Simpson reconstruction showed a correlation of 2D echo stroke volume with thermodilution (r = 0.89).
The simplified formula yielded a correlation of stroke volume with midpapillary cross-section (r = 0.90).
Cineangiography correlated well with 2D echo for stroke volume (r = 0.87) and ejection fraction (r = 0.97).

Structured PICO

Does two-dimensional echocardiography accurately measure left ventricular stroke volume compared to thermodilution and cineangiography in normal and ischemic closed-chest dogs?

Population

Closed-chest dogs before and one hour after proximal LAD occlusion (N=22; 14 normal, 8 ischemic)

Intervention

Two-dimensional echocardiography (2D echo) using Simpson's rule and a simplified volume formula

Comparator

Thermodilution and cineangiography measurements

Outcome

Correlation of left ventricular stroke volume measurementssurrogate

2D echocardiography provides accurate quantification of left ventricular stroke volume in both normal and ischemic states in a canine model.

Cite This Study

Guéret et al. (1981) studied this question.

synapsesocial.com/papers/6a12e6ec5bb7edc7189e71ab https://doi.org/10.1002/ccd.1810070304

Topics

Echocardiography

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Two‐dimensional echocardiographic assessment of left ventricular stroke volume: Experimental correlation with thermodilution and cineangiography in normal and ischemic states

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Two‐dimensional echocardiographic assessment of left ventricular stroke volume: Experimental correlation with thermodilution and cineangiography in normal and ischemic states

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

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