Key result
Brief dynamic therapy combined with antidepressants significantly improved remission rates on the HAM-D compared to supportive psychotherapy plus medication (75% vs. 12.5%) in major depression.
Why the study?
Does brief dynamic therapy added to pharmacotherapy improve depressive symptoms in outpatients with major depressive disorder compared to brief supportive psychotherapy?
Population
35 outpatients with major depressive disorder
Comparison
Brief dynamic therapy added to pharmacotherapy… vs Brief supportive psychotherapy added to…
Design
RCT, randomized
Follow-up
12 months
Authors
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Supports adjunctive brief dynamic therapy with antidepressants in major depression; extends evidence favoring specific over supportive psychotherapy.
RCT (n=35)
randomized
Does brief dynamic therapy added to pharmacotherapy improve depressive symptoms in outpatients with major depressive disorder compared to brief supportive psychotherapy?
Absolute Event Rate: 75% vs 12.5%
p-value: p=0.03
Brief dynamic therapy combined with antidepressants provides greater long-term symptom reduction and remission rates than supportive psychotherapy in major depressive disorder.
Maina et al. (2007) conducted an RCT in Major depressive disorder (n=35). Brief dynamic therapy (BDT) plus antidepressants vs. Brief supportive psychotherapy (BSP) plus antidepressants was evaluated on Remission rates on the HAM-D at 12 months (T3) (p=0.03). Brief dynamic therapy combined with antidepressants significantly improved remission rates on the HAM-D compared to supportive psychotherapy plus medication (75% vs. 12.5%) in major depression.
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