Diurnal Patterns of Blood Pressure, Heart Rate and Vasoactive Hormones in Normal Man
Population
5 healthy normotensive volunteers
Design
Cohort
Follow-up
24 hours
Authors
Discussion
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Member takes
Implication
Normative 24-hour intra-arterial BP values are lower than clinic readings in healthy volunteers; supports sympathetic linkage but should not yet change practice.
Structured PICO
P
Population
5 healthy normotensive volunteers
I
Intervention
Continuous intra-arterial pressure measurement and hourly venous hormone sampling (renin, angiotensin II, aldosterone, and catecholamines) for 24 hours under standardized conditions
O
Outcome
Diurnal patterns and relationships of arterial pressure and vasoactive hormonessurrogate
Continuous 24-hour blood pressure in healthy individuals is lower than typical clinic recordings, and arterial pressure fluctuations are closely coupled with sympathetic activity.
Cite This Study
Richards et al. (1986) studied this question.