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April 1, 2020Journal of Pharmacy Practice

Pharmacy Personnel’s Involvement in Transitions of Care of Intensive Care Unit Patients: A Systematic Review

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Key result

Pharmacy-driven interventions at ICU transitions consistently improve medication safety measures.

Why the study?

Medication error rates are high during ICU transfers, but limited data exist on whether pharmacy personnel-driven interventions improve medication safety compared to other team members or no intervention.

Do pharmacy personnel-driven interventions improve medication safety measures in patients transitioning into or out of the ICU?

Population

10 included investigations of patients transferred into or out of the ICU

Comparison

Pharmacy personnel-driven interventions vs interventions by other health-care team members or no intervention

Design

Systematic review

Authors

MRMikhaila RiceCleveland ClinicALAlyssa LearAtrium Medical CenteSKSandra L. Kane‐GillRutgers, The State University of New Jersey

Discussion

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Overview

May support pharmacy-driven ICU transition interventions for medication safety; extends evidence but leaves clinical outcome RCTs open.

Study Design

Type

Systematic Review

Structured PICO

Do pharmacy personnel-driven interventions improve medication safety measures in patients transitioning into or out of the ICU?

P
Population
Patients transferred into or out of the intensive care unit (ICU) across 10 included investigations.
I
Intervention
Pharmacy personnel- (pharmacist or pharmacy technician) driven interventions at transitions of care into or out of the intensive care unit (ICU)
C
Comparator
Interventions made by other health-care team members or no intervention
O
Outcome
Medication safety measuressafety

Pharmacy personnel-driven interventions during ICU transitions of care may improve medication safety, though high-quality randomized trials assessing clinical outcomes are still needed.

Limitations

  • Additional randomized and prospective trials with patient-centered outcomes that assess morbidity and mortality are needed
  • Limited data exist to address medication error rates in ICU transitions
  • Lack of randomized and prospective trials with patient-centered outcomes assessing morbidity and mortality

Cite This Study

Rice et al. (2020) conducted a systematic review in Intensive Care Unit Patients. Pharmacy personnel-driven interventions vs. Interventions made by other health-care team members or no intervention was evaluated on Medication safety measures. Pharmacy-driven interventions at ICU transitions of care significantly improved medication safety measures in all 4 studies evaluating the entire ICU patient population.

synapsesocial.com/papers/6a12fc4745487b7639a77dachttps://doi.org/10.1177/0897190020911524
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement2009 · 65,272 citations
  2. 2Adverse drug events in intensive care units: Risk factors, impact, and the role of team care2010 · 146 citations
  3. 3Analysis of risk factors for adverse drug events in critically ill patients*2011 · 154 citations
  4. 4Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement2009 · 83,697 citations
  5. 5Impact of an Antipsychotic Discontinuation Bundle During Transitions of Care in Critically Ill Patients2017 · 32 citations