Key result
Thermal mapping-guided ablation achieved noninducibility and long-term arrhythmia-free survival in 100% of patients with RVOT VT when standard induction techniques failed.
Why the study?
Does thermal mapping safely and effectively guide the ablation of right ventricular outflow tract tachycardia when standard induction techniques fail?
Observational (n=13)
Does thermal mapping safely and effectively guide the ablation of right ventricular outflow tract tachycardia when standard induction techniques fail?
Thermal mapping using subtherapeutic radiofrequency energy is an effective adjunctive technique to induce and map right ventricular outflow tract tachycardia when standard pacing and activation mapping fail.
May aid non-inducible RVOT VT ablation; hypothesis-generating and requires prospective validation before adoption.
BACKGROUND: Acute and long-term success of catheter ablation of right ventricular outflow tract tachycardia (RVOT VT) may be limited by the inability to reproduce the arrhythmia at the time of activation (AM) and pace mapping (PM). We have observed early initiation of the clinical VT when subtherapeutic radiofrequency (RF) energy was applied to the target area (TA), defined as a 2-cm(2) area around a pace match. We describe a novel approach using thermal mapping (TM) to guide the ablation of RVOT VT. METHODS: Thirteen patients (10 female, mean age 46.2 +/- 13.7 years) with symptomatic VT of left bundle branch block (LBBB) inferior axis morphology and no structural heart disease underwent standard electrophysiologic evaluation with PM (n = 13), AM (n = 13), and 3D noncontact mapping (n = 4). Thermal mapping was performed after standard techniques failed to induce stable sustained VT for mapping in all 13 patients: RF was applied for 5-10 seconds in the TA to achieve a tip temperature of 45-50 degrees C. At sites where morphologically consistent with the clinical VT was induced, RF was applied at target temperature between 50 and 60 degrees C for 30-60 seconds. TM was repeated before and after intravenous Isoproterenol infusion until no further VT could be induced by low temperature application. RESULTS: Noninducibility was achieved in all 13 patients. During a mean follow-up of 29 months (9-69 months), all patients remain arrhythmia-free, off antiarrhythmic medications. CONCLUSION: Thermal mapping is a safe and effective adjunctive technique for the mapping and ablation of RVOT VT when sustained tolerated clinical VT cannot be induced.
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Clyne et al. (2007) conducted an observational in Right ventricular outflow tract tachycardia (RVOT VT) (n=13). Thermal mapping-guided radiofrequency ablation was evaluated on Noninducibility and arrhythmia-free survival off antiarrhythmic medications. Thermal mapping-guided ablation achieved noninducibility and long-term arrhythmia-free survival in 100% of patients with RVOT VT when standard induction techniques failed.
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