An extensive overview on MicroRNAs and pandemic-prone viral diseases: The next frontier in predicting and mitigating pandemics

Niloofar Farsiu; Javad Charostad; Fatemeh Khodadadpour Mahani; Yousof Mir; Mohammad Rezaei Zadeh Rukerd; Nazanin Zeinali Nezhad; Amirhossein Shahpar; Mohammad Pardeshenas; Mohsen Nakhaie

doi:10.1016/j.meegid.2026.105963

May 1, 2026Infection Genetics and EvolutionOpen Access

An extensive overview on MicroRNAs and pandemic-prone viral diseases: The next frontier in predicting and mitigating pandemics

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Key Points

This work aims to explore the role of microRNAs in regulating viral diseases and their potential use in predicting pandemics.
Review of host and viral miRNAs affecting molecular pathways.
Analysis of circulating miRNA signatures as biomarkers.
Discussion of challenges facing miRNA-based diagnostics and therapeutics.
Circulating miRNA signatures have potential as biomarkers for viral infections.
Dysregulated miRNA networks significantly impact viral and human molecular pathways.
Omics platforms facilitate extensive profiling of miRNAs in the context of viral diseases.

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Implication

Overview highlights miRNAs' roles in viral diseases, suggesting potential for diagnostics and therapeutics.

Abstract

• Host and viral miRNAs regulate key molecular pathways. • Dysregulated miRNA networks influence viral and human-related pathways. • Circulating miRNA signatures show potential as biomarkers. • miRNA-based diagnostics and therapeutics still face critical challenges. • Omics platforms enable comprehensive profiling of miRNAs in viral infections.

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Cite This Study

Farsiu et al. (2026) studied this question.

synapsesocial.com/papers/6a13040913ab6312a8c0d866 https://doi.org/10.1016/j.meegid.2026.105963

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An extensive overview on MicroRNAs and pandemic-prone viral diseases: The next frontier in predicting and mitigating pandemics

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

An extensive overview on MicroRNAs and pandemic-prone viral diseases: The next frontier in predicting and mitigating pandemics

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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