Effects of Autoantibodies to the Insulin Receptor on Isolated Adipocytes

Puntos clave

• The central aim is to explore the impact of autoantibodies to the insulin receptor on adipocyte function.
• Evaluated the role of autoantibodies in stimulating glucose transport in isolated adipocytes.
• Assessed glucose incorporation into lipid and glycogen.
• Autoantibodies stimulated 2-deoxy-glucose transport in isolated adipocytes.
• Increased glucose incorporation into lipid and glycogen was observed.