Molecular genetic analysis uncovers the role of the WOR1 promoter in Candida albicans switching, suggesting a critical control point for mating and colonization.
Candida albicans , the most pervasive fungal pathogen colonizing humans, undergoes a phenotypic transition between a white and opaque phenotype. The unique opaque phenotype is necessary for mating and colonization of the lower gastrointestinal tract.
No takes yet. Share an insight, caveat, or question.
Conway et al. (2021) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: