Key result
The Wavelet algorithm is influenced by myopotential interference when the Can-RV coil EGM is less than 5 mV (AUC 0.89), leading to inappropriate detections in 5% of patients.
Why the study?
Does myopotential interference influence the Wavelet discrimination algorithm in outpatients with an ICD?
Observational (n=40)
Does myopotential interference influence the Wavelet discrimination algorithm in outpatients with an ICD?
The Wavelet algorithm in ICDs is susceptible to myopotential interference when the Can-RV coil EGM is less than 5 mV, which can lead to inappropriate shocks.
Answers are grounded in this paper and cite their sources.
May warrant EGM amplitude checks before relying on Wavelet; leaves open need for prospective mitigation studies.
BACKGROUND: Wavelet is a morphology-based algorithm for detecting ventricular tachycardia. The electrogram (EGM) source of the Wavelet algorithm is nominally programmed with the Can-RV coil configuration, which records a far-field ventricular potential. Therefore, it may be influenced by myopotential interference. METHODS: We performed a retrospective review of 40 outpatients who had an implantable cardioverter-defibrillator (ICD) with the Wavelet algorithm. The percent-match score of the Wavelet algorithm was measured during the isometric chest press by pressing the palms together. We classified patients with percent-match scores below 70% due to myopotential interference as positive morphology change, and those with 70% or more as negative morphology change. Stored episodes of tachycardia were evaluated during the follow-up. The cut-off value of the Can-RV coil EGM was 5 mV (area under curve, 0.89). Inappropriate detections caused by myopotential interference occurred in two patients (5%) during a mean follow-up period of 49 months, and one of them received an inappropriate ICD shock. These patients had exhibited positive morphology change. CONCLUSIONS: The Wavelet algorithm is influenced by myopotential interference when the Can-RV coil EGM is less than 5 mV.
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Mizukami et al. (2016) conducted an observational in Outpatients with an implantable cardioverter-defibrillator (ICD) (n=40). Wavelet discrimination algorithm was evaluated on Inappropriate detections caused by myopotential interference (AUC 0.89, p==0.0015). The Wavelet algorithm is influenced by myopotential interference when the Can-RV coil EGM is less than 5 mV (AUC 0.89), leading to inappropriate detections in 5% of patients.
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