Key result
High visceral adipose tissue linked to ~6-fold higher new-onset diabetes risk in primary aldosteronism.
Why the study?
Patients with primary aldosteronism have a high prevalence of diabetes, but the relationship between visceral adipose tissue and new-onset diabetes mellitus in these patients remains unclear.
Does high visceral adipose tissue predict new-onset diabetes mellitus in patients with primary aldosteronism?
Population
342 patients with primary aldosteronism
Comparison
Levels of visceral adipose tissue and abdominal adiposity indexes
Design
Prospective cohort study
Follow-up
Mean follow-up of 7.4 years
Authors
Loading...
May warrant closer NODM monitoring in primary aldosteronism with high VAT; leaves open causality and intervention effects.
Cohort (n=342)
Does high visceral adipose tissue predict new-onset diabetes mellitus in patients with primary aldosteronism?
Effect estimate: OR 6.09
p-value: p=0.005
In patients with primary aldosteronism, high visceral adipose tissue at diagnosis is a strong predictor of developing new-onset diabetes mellitus over long-term follow-up.
Chu et al. (2024) conducted a cohort in Primary aldosteronism (n=342). High visceral adipose tissue (VAT) vs. Low VAT was evaluated on New-onset diabetes mellitus (NODM) (OR 6.09, p=0.005). High visceral adipose tissue significantly increased the risk of new-onset diabetes mellitus in patients with primary aldosteronism over a mean follow-up of 7.4 years (OR 6.09; p=0.005).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: