Key result
This review summarizes the clinical features, diagnostic investigations, and recent advances in the epidemiology and management of various autonomic peripheral neuropathies.
Knowledge and recognition of clinical features and appropriate testing facilitate accurate diagnosis and management of autonomic neuropathies.
Facilitates accurate diagnosis and management of autonomic neuropathies; summarizes advances while leaving key management questions open for prospective study.
PURPOSE OF REVIEW: This article provides a summary of the autonomic neuropathies, including neuropathies associated with diabetes mellitus, neuropathies due to amyloid deposition, immune-mediated autonomic neuropathies (including those associated with a paraneoplastic syndrome), inherited autonomic neuropathies, and toxic autonomic neuropathies. The presenting features, diagnostic investigations, and natural history of these neuropathies are discussed. RECENT FINDINGS: Recent findings in autonomic peripheral neuropathy include data on the epidemiology and atypical presentations of diabetic autonomic neuropathy, treatment-induced neuropathy of diabetes mellitus, the presentation of immune-mediated neuropathies, and advances in hereditary neuropathy associated with amyloidosis and other hereditary neuropathies. SUMMARY: Knowledge and recognition of the clinical features of the autonomic neuropathies, combined with appropriate laboratory and electrophysiologic testing, will facilitate accurate diagnosis and management.
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Roy Freeman (2020) conducted a review in Autonomic peripheral neuropathy. This review summarizes the clinical features, diagnostic investigations, and recent advances in the epidemiology and management of various autonomic peripheral neuropathies.
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