Key result
Classical and generalized sensitivity analyses were compared and applied to a cardiovascular system model simulating the transition to aerobic exercise using optimal control.
This paper discusses and compares classical and generalized sensitivity analysis applied to a computational model of the cardiovascular system during aerobic exercise.
Generalized sensitivity analysis extends classical methods for cardiovascular exercise models; leaves open prospective clinical validation.
In this paper we consider the sensitivity analysis of a model of the cardiovascular system (CVS) simulating the transition to aerobic exercise and where the control for the system is implemented via an optimal control. Classical and generalized sensitivity analysis are discussed and compared and their application to the CVS model is analyzed.
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Kappel et al. (2006) studied this question. Classical and generalized sensitivity analyses were compared and applied to a cardiovascular system model simulating the transition to aerobic exercise using optimal control.
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