Why the study?
Is a depressive emotional state associated with ventricular arrhythmias in men with or without ischemic heart disease?
Is a depressive emotional state associated with ventricular arrhythmias in men with or without ischemic heart disease?
A depressive emotional state may contribute to the formation of ventricular arrhythmias in healthy men without underlying cardiovascular disease.
No immediate clinical implications for arrhythmia management; hypothesis-generating association in healthy men requires longitudinal confirmation.
The association between psychological characteristics and ventricular arrhythmias was investigated in 150 men (50 with manifest IHD, 50 with risk indicators of IHD and 50 healthy men). Arrhythmias were recorded with 24-hour Holter monitoring. Psychological characteristics were assessed by the Emotions Profile Index and the Structured Interview for pattern A behaviour. A depressive emotional state was associated with prognostically severe ventricular arrhythmia in healthy men, but not in men with overt IHD or risk indicators of IHD. When clinical characteristics and age were taken into account, depressiveness was-among healthy men-the second most important factor after high age. The results suggest that-in absence of IHD or other cardiovascular disease-a depressive emotional state may participate in the formation of ventricular arrhythmia.
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Orth‐Gomér et al. (1980) studied this question.
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