Key result
Echocardiography detects baseline IVC dilation in ~96% of type 1 CRS ICU patients, improving post-treatment.
Why the study?
No study has evaluated the reliability of transthoracic echocardiography to assist in the diagnosis and optimization of type 1 cardiorenal syndrome.
Observational (n=27)
No
Transthoracic echocardiography, specifically monitoring IVC diameter and RV/LV diameter ratio, is a useful non-invasive tool for tracking treatment response in ICU patients with type 1 cardiorenal syndrome.
May support serial echocardiography to track congestion relief in type 1 CRS; leaves open impact on ICU outcomes.
BACKGROUND: Type-one cardiorenal syndrome (CRS) is defined by acute decompensated heart failure leading to secondary acute kidney injury. No study evaluates the reliability of transthoracic echocardiography as a help tool for diagnosis and optimization of CRS. Therefore, the aim of this study was to assess echocardiographic parameters in patients with CRS in the Intensive Care Unit. METHODS: We conducted an observational, prospective, single-center study in the ICU department of a general hospital. Patients admitted in the ICU and presenting with type 1 CRS were included. Transthoracic echocardiography was performed at baseline and at day end after treatment by the same trained operator for the same patients. We report various echocardiographic indices at these two timepoints. RESULTS: Twenty-seven patients were included. At baseline 96.3% of patients had signs of congestion (IVC dilation >2 cm), 76% had an altered S-wave (<11.5 cm/s), 72.73% had an altered TAPSE (<17 mm), 85.19% had an elevated RV/LV diameter ratio (>0.6). Between baseline and D end, IVC size and, the number of patients with an elevated RV/LV diameter ratio significantly decreased. Weight decreased, whereas natriuresis significantly increased, and the amount of vasopressors support decreased. Diuresis, and S-wave velocity showed non-significant changes. CONCLUSIONS: Main echocardiographic findings at baseline in patients with type 1 CRS consist of a right ventricular dysfunction associated an IVC dilation. We report that weight, RV/LV diameter ratio, and IVC diameter might constitute good follow-up parameters to monitor treatment response.
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GENEIX et al. (2021) conducted an observational in Type 1 cardiorenal syndrome (n=27). Transthoracic echocardiography was evaluated on Echocardiographic parameters. Transthoracic echocardiography in ICU patients with type 1 CRS identified baseline IVC dilation in 96.3% of patients, with IVC size and RV/LV diameter ratio significantly decreasing after treatment.
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