Key result
Mitral annular disjunction >=5 mm is linked to ~296% greater arrhythmia risk on cardiac MRI.
Why the study?
Does the presence and length of mitral annular disjunction (MAD) on cardiac MRI associate with a higher prevalence of arrhythmias in patients undergoing cardiac MRI?
Observational (n=2,611)
Yes
Does the presence and length of mitral annular disjunction (MAD) on cardiac MRI associate with a higher prevalence of arrhythmias in patients undergoing cardiac MRI?
Effect estimate: OR 2.84 (95% CI 1.99-4.04)
Absolute Event Rate: 40.1% vs 17.9%
p-value: p=<.001
Mitral annular disjunction is a frequent incidental finding on cardiac MRI, but a length ≥5 mm and coexistence with bileaflet mitral valve prolapse are associated with a significantly higher risk of arrhythmias.
Mitral annular disjunction (MAD) was a frequent incidental finding at cardiac MRI examinations performed for various clinical indications; longer MAD length and coexisting bileaflet mitral valve prolapse were associated with a higher prevalence of arrhythmia.
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Palmisano et al. (2024) conducted an observational in Various clinical indications for cardiac MRI (n=2,611). Mitral annular disjunction (MAD) vs. Absence of MAD was evaluated on Presence of arrhythmia (OR 2.84, 95% CI 1.99-4.04, p=<.001). A mitral annular disjunction length of 5 mm or greater independently predicted arrhythmia (OR 3.96) in patients undergoing cardiac MRI.
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