Key result
Autopsy links combined AAOCA, BAV, and PFO to sudden post-partum cardiac death.
Why the study?
Some congenital cardiac defects remain undiagnosed and asymptomatic until adulthood, and the co-occurrence of patent foramen ovale, anomalous aortic origin of the left main coronary artery, and bicuspid aortic valve is rarely seen.
Case Report (n=1)
This case highlights a rare association of anomalous aortic origin of the coronary artery with bicuspid aortic valve and patent foramen ovale leading to sudden death in a post-partum female.
This rare triad warrants consideration in post-partum sudden death; hypothesis-generating for screening studies.
Modern techniques have enabled routine diagnosis of congenital cardiac defects, notwithstanding, there will be some that remain undiagnosed and asymptomatic until adulthood. But this is rarely the case with the patent foramen ovale, with the anomalous aortic origin of the left main coronary artery and bicuspid aortic valve. This case describes the sudden death of a female in her post-partum period due to cardiac tamponade following a ruptured aneurysm of the coronary artery at its origin at the sinus of Valsalva. Autopsy shows patent foramen ovale findings and anomalous aortic origin of coronary artery (AAOCA) and bicuspid aortic valve. The association of AAOCA with bicuspid aortic valve and patent foramen ovale is rare.
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Thube et al. (2022) conducted a case report in Anomalous aortic origin of coronary artery with bicuspid aortic valve (n=1). Anomalous aortic origin of the coronary artery combined with a bicuspid aortic valve and patent foramen ovale was identified on autopsy as the cause of sudden death in a post-partum female.
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