Why the study?
Do patients with crescendo unstable angina have more extensive coronary disease and lower ejection fractions compared to those with recent onset unstable angina?
Do patients with crescendo unstable angina have more extensive coronary disease and lower ejection fractions compared to those with recent onset unstable angina?
Patients with crescendo unstable angina have more extensive coronary disease and lower ejection fractions than those with recent onset angina, which may explain their poorer prognosis.
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Crescendo angina may refine unstable angina risk stratification; leaves open whether disease extent drives outcomes in prospective studies.
Among patients with unstable angina pectoris, those with crescendo angina seem to be at high risk for death and myocardial infarction. We reviewed the clinical, arteriographic, and hemodynamic findings in 218 consecutive catheterized patients with unstable angina. Unstable angina was defined as ischemic cardiac pain at rest associated with transient ECG changes but no evidence for acute myocardial infarction. Patients were divided into two groups according to the duration of symptoms: 134 patients with crescendo angina (new, or increasing, rest pain with previous ischemic symptoms present for more than three months) and 84 with recent onset angina (symptoms present for less than three months). Compared with patients with recent onset symptoms, patients with crescendo angina had more extensive coronary disease and lower ejection fractions, which may explain their poor prognosis.
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Gary D. Plotnick (1980) studied this question.
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