Key result
Recommendations from a national conference suggest that for over two decades, many patients in North America could have been treated as effectively but more safely using lower doses of oral anticoagulants.
Why the study?
Are the historically prescribed doses of warfarin by American physicians unnecessarily high, and could lower doses be equally effective and safer?
Population
Patients in North America receiving oral anticoagulants (vitamin K antagonists)
Comparison
Lower doses of oral anticoagulants vs Historically prescribed higher doses
Design
Editorial
Authors
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Highlights a consensus discussion suggesting that historically prescribed doses of warfarin in North America may have been unnecessarily high, advocating for lower, safer doses.
Are the historically prescribed doses of warfarin by American physicians unnecessarily high, and could lower doses be equally effective and safer?
Highlights a consensus discussion suggesting that historically prescribed doses of warfarin in North America may have been unnecessarily high, advocating for lower, safer doses.
J. Hirsh (1987) conducted an editorial in Anticoagulant therapy. Oral anticoagulants (warfarin) vs. Higher doses was evaluated. Recommendations from a national conference suggest that for over two decades, many patients in North America could have been treated as effectively but more safely using lower doses of oral anticoagulants.
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