Key result
Radical nephrectomy plus epirubicin and ifosfamide prevents recurrence in a primary renal synovial sarcoma case.
Why the study?
To provide clinical reference regarding the imaging findings and diagnosis of the rare disease primary renal synovial sarcoma.
Case Report (n=1)
No
Radical surgical resection combined with epirubicin and ifosfamide chemotherapy is a safe and effective treatment option for primary renal synovial sarcoma.
Supports multimodality therapy for primary renal synovial sarcoma; hypothesis-generating and should not yet alter practice.
This case report describes a 53-year-old male patient with primary renal synovial sarcoma. He initially presented with intermittent pain in the lumbar and abdominal regions. Imaging revealed a left renal mass measuring approximately 13.3 cm × 11.6 cm. After radical left nephrectomy, pathological diagnosis was confirmed through immunohistochemical analysis and genetic testing, which identified an SS18-SSX2 fusion, leading to a definitive diagnosis of primary renal synovial sarcoma. Postoperatively, the patient received chemotherapy with epirubicin combined with ifosfamide. Follow-up showed no significant evidence of metastasis or recurrence. This report aims to provide clinical reference regarding the imaging findings and diagnosis of this rare disease, primary renal synovial sarcoma.
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Li et al. (2026) conducted a case report in Primary renal synovial sarcoma (n=1). Radical left nephrectomy and chemotherapy (epirubicin and ifosfamide) was evaluated on Tumor recurrence or metastasis. Radical left nephrectomy followed by four cycles of epirubicin and ifosfamide resulted in no recurrence or metastasis in a 53-year-old male with primary renal synovial sarcoma.
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