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May 25, 2026BMC OphthalmologyOpen Access

Risk factors for ocular complications in HIV/AIDS patients: a retrospective analysis of ophthalmology consultations in a tertiary hospital in Central China

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Authors

RZRenfan ZhangTZTian ZhengXCXiaomin Chen

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Overview

Retrospective analysis identifies predictors of ocular lesions in HIV-positive inpatients, suggesting early ophthalmic referrals.

Key Points

  • This analysis aims to quantify the incidence of ocular complications and identify predictors among HIV-positive patients in Central China.
  • Retrospective analysis of HIV-1-positive inpatients aged ≥ 18 years
  • Standardized ophthalmic screening conducted from November 2019 to June 2023
  • Binary logistic regression models used to assess factors associated with fundus lesions.
  • Out of 345 patients, 117 (34%) had fundus lesions, primarily opportunistic infections (35.9%) and HIV-related microangiopathy (59.8%)
  • Median CD4+ T cell count was lowest in the microangiopathy group at 18.5 cells/µL, while syphilis-related uveitis had the highest at 166 cells/µL
  • Age, nadir CD4+ < 50 cells/µL, and symptomatic visual loss were identified as independent risk factors for ocular complications.

Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/6a13e6b30e02ee3982d319d7https://doi.org/10.1186/s12886-026-04916-4
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