Key result
Radiofrequency-powered transseptal puncture results in life-threatening descending aorta perforation during LAAC.
Why the study?
Aortic root injury during transseptal puncture is a recognized complication, but injury to the descending aorta had not previously been described.
Case Report (n=1)
Radiofrequency-powered systems for transseptal puncture can cause life-threatening descending aorta perforation, highlighting the need for caution, particularly in patients with an interatrial septum aneurysm.
May warrant procedural caution in LAA closure; leaves open optimal imaging and technique refinements.
BACKGROUND: Aortic root injury during transseptal puncture (TSP) is a rare but well-recognized complication. However, injury to the descending aorta has not previously been described in this context. CASE SUMMARY: A 57-year-old woman underwent left atrial appendage closure. During TSP using the VersaCross Connect radiofrequency-powered system and a 15-F steerable sheath, an unrecognized perforation of the descending aorta occurred. Despite repeated transthoracic echocardiograms showing no pericardial effusion and initial hemodynamic stability, she subsequently developed a mediastinal hematoma and bilateral pleural effusion. Management required an emergency percutaneous thoracic endovascular aortic repair, followed by surgical evacuation of the hematoma. DISCUSSION: Excessive tenting during radiofrequency-powered TSP, related to interatrial septum aneurysm, resulted in injury to the descending aorta with life-threatening consequences. TAKE-HOME MESSAGE: Radiofrequency-powered systems for TSP have enhanced tissue penetration capability and should therefore be used with caution, particularly in the presence of an interatrial septum aneurysm and atypical echocardiographic windows.
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Bini et al. (2026) conducted a case report in Left atrial appendage closure (n=1). Transseptal puncture using VersaCross Connect radiofrequency-powered system was evaluated on Descending aorta perforation. Radiofrequency-powered transseptal puncture resulted in an unrecognized, life-threatening perforation of the descending aorta in a 57-year-old woman undergoing left atrial appendage closure.
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