Key result
Arterial hypertension in pediatric obesity linked to higher post-load glucose and HOMA-IR.
Why the study?
Coexistence of arterial hypertension in children with obesity increases morbidity, but its role as an indicator of coexisting metabolic complications is less known.
Is arterial hypertension associated with worse metabolic profiles in pediatric patients with obesity?
Observational (n=534)
Is arterial hypertension associated with worse metabolic profiles in pediatric patients with obesity?
Absolute Event Rate: 6.3% vs 5.7%
p-value: p=0.000041
In pediatric patients with obesity, the presence of arterial hypertension is associated with worse insulin resistance and glucose tolerance, serving as a potential indicator for metabolic complications.
Supports closer metabolic monitoring in hypertensive obese youth; leaves open whether hypertension precedes or reflects insulin resistance.
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Stępniewska et al. (2022) conducted an observational in Pediatric obesity (n=534). Arterial hypertension vs. No arterial hypertension was evaluated on Post-load glucose level (p=0.000041). Arterial hypertension in pediatric patients with obesity was associated with higher post-load glucose (6.3 vs 5.7, p=0.000041) and HOMA-IR (4.5 vs 4.0, p=0.029) compared to those without it.
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