Key result
Basal septal bulge linked to new-onset conduction disturbance after TAVR with ACURATE neo/neo2.
Why the study?
The impact of basal septal bulge on new-onset conduction disturbance after transcatheter aortic valve replacement using ACURATE neo/neo2 remains unclear.
Does basal septal bulge predict new-onset conduction disturbance in patients undergoing TAVR with ACURATE neo/neo2?
Cohort (n=518)
No
Does basal septal bulge predict new-onset conduction disturbance in patients undergoing TAVR with ACURATE neo/neo2?
Basal septal bulge is a significant predictor of new-onset conduction disturbance following TAVR with the ACURATE neo/neo2 valve, allowing for risk stratification.
May aid pre-TAVR conduction risk stratification with ACURATE neo/neo2; leaves open need for prospective validation before practice change.
Background: New-onset conduction disturbance (CD) is a common complication of transcatheter aortic valve replacement (TAVR). Recently, basal septal bulge (BSB) has been reported as a predictor of CD. However, the impact of BSB on CD using ACURATE neo/neo2 remains unclear. We hypothesized that the left bundle branch could be damaged in patients with large BSB even by low radial force. This study investigated the predictors of CD after TAVR using ACURATE neo/neo2 and the impact of BSB on CD. Methods: We retrospectively analyzed 518 patients who underwent TAVR with ACURATE neo/neo2 in a single center. New-onset CD was defined as 30-day new permanent pacemaker implantation or new left bundle branch block lasting until discharge. The endpoints were the predictors of CD and the effect of BSB. Conclusions: BSB was significantly associated with CD in ACURATE neo/neo2, and CD risk could be stratified using baseline factors in patients with large BSB. These findings might be beneficial for periprocedural management and TAVR strategy.
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Sugiyama et al. (2025) conducted a cohort in Transcatheter aortic valve replacement (n=518). Basal septal bulge was evaluated on New-onset conduction disturbance (30-day new permanent pacemaker implantation or new left bundle branch block lasting until discharge) (p=< 0.0001). Basal septal bulge was significantly associated with new-onset conduction disturbance after transcatheter aortic valve replacement using ACURATE neo/neo2 (P<0.0001).
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