Why the study?
Does mitral repair using only a semi-rigid annuloplasty band improve valve function and geometry in patients with Barlow's disease with multiple central jets and no chordal rupture?
Population
40 patients with Barlow's disease featuring multiple large central jets without chordal rupture.
Design
Cohort
Follow-up
mean 4.7 ± 3.2 years
Key result
Mitral repair using only a semi-rigid annuloplasty band in Barlow's disease patients without chordal rupture resulted in 0 deaths or reoperations over a mean follow-up of 4.7 years.
Authors
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Supports annuloplasty band alone in this Barlow subgroup; hypothesis-generating, needs RCTs before practice change.
Cohort (n=40)
Does mitral repair using only a semi-rigid annuloplasty band improve valve function and geometry in patients with Barlow's disease with multiple central jets and no chordal rupture?
In a specific sub-population of Barlow's disease patients without chordal rupture, mitral repair using only a semi-rigid annuloplasty band safely and effectively restores valve function and geometry.
Paulis et al. (2015) conducted a cohort in Barlow's disease with severe mitral regurgitation (n=40). Mitral repair using only a semi-rigid annuloplasty band was evaluated on Death, reoperation, and echocardiographic changes in valvular and ventricular morphology. Mitral repair using only a semi-rigid annuloplasty band in Barlow's disease patients without chordal rupture resulted in 0 deaths or reoperations over a mean follow-up of 4.7 years.