Key result
Changing from a sitting to a supine position significantly altered intraocular pressure in healthy adults (p<0.001), though the clinical relevance of this body position effect appears marginal.
Why the study?
To determine differences in intraocular pressure between supine and sitting positions, and assess the effects of age and cardiovascular parameters.
Does body position affect intraocular pressure in healthy adults?
Cross-Sectional (n=72)
Does body position affect intraocular pressure in healthy adults?
p-value: p=<0.001
Body position and heart rate have statistically significant but clinically marginal effects on intraocular pressure in healthy adults.
Body position effects on IOP warrant no protocol changes in healthy adults; leaves open relevance for glaucoma monitoring.
Objectives: The main goal of this research was to determine the differences between the values of intraocular pressure (IOP) in the supine and sitting positions, and to assess the effect of age and cardiovascular parameters. Methods: Seventy-two healthy adults were enrolled and classified into age groups: 20–30 years (group A), 31–40 years (group B), and 41–71 years (group C). Corneal biometry and cardiovascular parameters, such as heart rate (HR), were measured. IOP measurements were taken in the sitting position (IOP S ) and in the supine position (IOP L ) using the iCare ® Pro tonometer. Results: A significant difference between the IOP S and IOP L in the entire cohort was found ( p < 0.001). Regarding the age subgroups, a significant difference ( p < 0.001) between the IOP S and IOP L was obtained in group A (2.6 ± 1.6 mmHg) and group C (1.5 ± 1.3 mmHg). There were no significant differences in the IOP S between groups. The highest IOP values were obtained for group A. The correlations between HR and IOP S are statistically significant for group A and group B, and for HR and IOP L-S for group B only. Multivariate analysis showed that HR has a significant influence on the difference in IOP in the two body positions. Conclusion: A statistically significant difference between the effect of age and the values of IOP S and IOP L was shown. Cardiovascular parameters showed some relevant statistical dependencies, but with a rather marginal significance in young people. The influence of body position for the measurement of IOP for healthy subjects does not seem to matter, despite the fact that there are some dependencies that are statistically significant.
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Sobczak et al. (2021) conducted a cross-sectional in Healthy adults (n=72). Supine position vs. Sitting position was evaluated on Difference in intraocular pressure (IOP) between supine and sitting positions (p=<0.001). Changing from a sitting to a supine position significantly altered intraocular pressure in healthy adults (p<0.001), though the clinical relevance of this body position effect appears marginal.
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