Key result
Onset of active myocardial force generation strongly correlated with intramyocardial electromyograms (r=0.93) and was superior to shortening velocity and strain for assessing electrical dyssynchrony.
Why the study?
Does onset of active myocardial force generation (AFG) accurately measure electrical dyssynchrony compared to shortening velocity and strain in anesthetized dogs?
Does onset of active myocardial force generation (AFG) accurately measure electrical dyssynchrony compared to shortening velocity and strain in anesthetized dogs?
Effect estimate: r=0.93
Onset of active myocardial force generation is an accurate marker of myocardial electrical activation and is superior to shortening velocity and strain for identifying electrical dyssynchrony.
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AFG onset merits exploration in dyssynchrony models; leaves open human validation before clinical consideration.
Russell et al. (2010) studied Left ventricular electrical dyssynchrony. Onset of active myocardial force generation (AFG) vs. Shortening velocity and strain was evaluated on Correlation and agreement with intramyocardial electromyograms (IM-EMG) for measuring electrical dyssynchrony (r=0.93). Onset of active myocardial force generation strongly correlated with intramyocardial electromyograms (r=0.93) and was superior to shortening velocity and strain for assessing electrical dyssynchrony.
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