Key result
Cardiac resynchronization improved symptoms, quality of life, and reduced death risk in heart failure patients, complementing standard pharmacologic therapy.
Why the study?
Does cardiac resynchronization reduce the composite of death or unplanned hospitalization for a major cardiovascular event in patients with NYHA class III/IV heart failure, left ventricular systolic dysfunction, and cardiac dyssynchrony?
Does cardiac resynchronization reduce the composite of death or unplanned hospitalization for a major cardiovascular event in patients with NYHA class III/IV heart failure, left ventricular systolic dysfunction, and cardiac dyssynchrony?
In patients with moderate or severe heart failure and cardiac dyssynchrony, adding cardiac resynchronization to standard pharmacologic therapy significantly reduces the risk of death and major cardiovascular hospitalizations.
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Supports adding cardiac resynchronization to standard therapy in eligible heart failure patients; confirms and extends prior trial evidence on outcomes.
Cleland et al. (2005) studied this question. Cardiac resynchronization improved symptoms, quality of life, and reduced death risk in heart failure patients, complementing standard pharmacologic therapy.
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