New insights into cardiac resynchronization therapy
Why the study?
Does cardiac resynchronization therapy improve outcomes in patients with heart failure and ventricular dyssynchrony?
Population
Patients with symptomatic heart failure despite optimal medical therapy, prolonged QRS interval, and LVEF <=…
Comparison
Cardiac resynchronization therapy with or… vs Standard pharmacologic therapy
Design
Review
Authors
Discussion
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Member takes
Implication
Supports CRT consideration in eligible HF patients; leaves open refinement of selection criteria and response prediction.
Structured PICO
Does cardiac resynchronization therapy improve outcomes in patients with heart failure and ventricular dyssynchrony?
P
Population
Patients with symptomatic heart failure despite optimal medical therapy, prolonged QRS interval, and LVEF <= 35%
I
Intervention
Cardiac resynchronization therapy (CRT) with or without a defibrillator
C
Comparator
Standard pharmacologic therapy
O
Outcome
Mortality, morbidity, functional status, and quality of life
This review highlights the established benefits of cardiac resynchronization therapy in reducing mortality and improving quality of life for patients with symptomatic heart failure, reduced LVEF, and prolonged QRS.
Cite This Study
Andrew E. Epstein (2009) studied this question.